Home2 Suites By Hilton Sioux Falls Sanford Medical Center Exterior photoHome2 Suites By Hilton Sioux Falls Sanford Medical Center Interior photoHome2 Suites By Hilton Sioux Falls Sanford Medical Center Exterior photo

Home2 Suites By Hilton Sioux Falls Sanford Medical Center

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Check rooms and rates
From$166 /night
Check-in
03Sept
Check-out
04Sept
Rooms and Guests2 Guests, 1 Room
Key details

About the Hotel

1120 S Grange Avenue, Sioux Falls, 57105
-
Near the Denny Sanford Premier Center
Great
8.9
9.3
/10
4.5
/5

All-suite hotel with skywalk connection to Sanford Medical Center

Amenities & Facilities

The hotel offers a Spin2Cycle facility combining laundry and fitness equipment, an indoor saline swimming pool, and a hot tub. A 24-hour fitness center is available for guests, and a complimentary hot breakfast buffet is served daily. Event facilities span 950 square feet, and a business center provides meeting room access.

Suites & Accommodations

Each suite includes a fully equipped kitchen with a full-size refrigerator, a flat-screen TV, and a sofa bed. Rooms are pet-friendly and offer a work desk and free toiletries. The hotel provides free grocery delivery directly to guest suites.

Location & Access

The hotel is connected to Sanford Medical Center via a secure skywalk, allowing direct access without going outside. It is located near the University of Sioux Falls and Falls Park, and Sioux Falls Regional Airport is 4 km away. The well-lit skywalk provides safe passage after dark.

Business & Medical Travel

An on-site business center and meeting room are available for corporate guests, with express check-in/check-out and luggage storage. The 24-hour front desk offers fax/photocopying services and late check-out flexibility where available. The hotel is designed for medical professionals and families visiting patients, with a target audience of business travelers looking for extended stays.

Family & Pet-Friendly Stays

Family rooms are air-conditioned and include kitchen facilities, while pet-friendly rooms accommodate dogs with ample green spaces nearby. The indoor saline swimming pool and hot tub are available for all guests, and a complimentary hot breakfast buffet is served daily. The hotel offers a quiet neighborhood with sidewalks and a designated shelter for smokers.

“This all-suite hotel caters especially well to those visiting the Sanford Medical Center, with thoughtful touches extending to guest room design and even staff interactions. I appreciate the hotel's focus on extended stays, evidenced by in-room kitchens and the practical Spin2Cycle-a combined laundry and fitness area. Its free grocery delivery and late check-out flexibility, where available, enhance the experience.”
Hotel logo
James DavidEditor-in-Chief at Dogfriendly-hotels

Select your room type

The hotel provides many room choices—family rooms, doubles, and pet-friendly suites—with breakfast, free cancellation, and special offers
  • King Studio Suite Non-Smoking
    2 persons
    40 m²
    1 King-size bed
    Air conditioning
    Heating
  • Queen Studio Two Queen Beds Non-Smoking
    2 persons
    40 m²
    2 King Size Beds
    Air conditioning
    Heating
  • King Studio Suite Hearing Access or Non-Smoking
    2 persons
    40 m²
    1 King-size bed
    Air conditioning
    Heating
Show all rooms

Rates & availability calendar

See current prices and availability for your chosen dates!
September 2026 - September 2027
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Check-in/ Check-out

Facilities

Hotels feature amenities designed to keep both you and your pet comfortable
Facilities: Perfect
9.1/10Review score

General

  • No smoking on site
  • Wi-Fi
  • Free parking
  • Off-site car park
  • 24-hour reception
  • Express check-in/ -out
  • Pets allowed
  • Rooms/ Facilities for disabled
  • Wheelchair access
  • Luggage storage
  • Lift

Sports & Fitness

  • Fitness centre

Services

  • Laundry

Business

  • Business centre
  • Fax/Photocopying

Spa & Leisure

  • Indoor swimming pool
  • Jacuzzi

Room features

  • Air conditioning
  • Heating
  • Sitting area
  • Tea and coffee facilities
  • Ironing facilities

Bathroom

  • Free toiletries

Media

  • Flat-screen TV
  • AM/FM alarm clock

Room decor

  • Curtains
Show more

Location

1120 S Grange Avenue, Sioux Falls, 57105
Explore Sioux Falls
Explore Sioux Falls
  • Top Attractions
  • Activities
  • Dining
  • Entertainment
Great Plains Zoo & Delbridge Museum
25 minutes walking
Home to over 1,000 animals, this zoo offers a unique museum featuring fossil exhibits. Family-friendly with seasonal events.
Michelangelo's David Replica
15 minutes walking
A stunning reproduction of Michelangelo's masterpiece located in a beautiful park. A perfect photo opportunity.
The Pettigrew Home and Museum
20 minutes walking
A historical house museum dedicated to the life of a local statesman. Features Victorian-era artifacts and guided tours.
Falls Park
30 minutes walking
A scenic park showcasing the stunning waterfalls of the Big Sioux River, with walking paths and picnic areas.
Sioux Falls Bike Trail
25 minutes walking
Scenic trails perfect for biking and walking, featuring views of nature and the city. Bike rentals available nearby.
Midco Aquatic Center
16 minutes walking
An indoor water park with slides and pools, great for families. Open year-round, check for specific attraction hours.
Azteca
13 minutes walking
A vibrant Mexican restaurant known for its flavorful enchiladas and margaritas. Vegetarian options available.
Toppers Pizza
13 minutes walking
Casual pizzeria offering a variety of unique pizzas and sides. Ideal for a quick meal, takeout available.
Lucky Lady Casino
15 minutes walking
A local casino offering a range of games and live entertainment. Great for an evening out with friends.
Downtown Sioux Falls
20 minutes walking
Vibrant area featuring shops, cafes, and live music venues. Perfect for a relaxed evening stroll.
Local transport and travel tips
  • City Centre
    Sioux Falls 10 min  ·  800 m
  • Airports
    Sioux Falls Regional (FSD) 12 min  ·  8 km
    Stronsay (soy) 134 min  ·  88.7 km
Want access to early-bird pet-friendly hotel deals?
Access exclusive discounts today!
Check Rates
Property information and rules
Check-in
from 15:00-23:59
Check-out
until 12 pm
Guest Parking
Public parking is possible on site for free.
Internet
Wireless internet is available in the entire hotel for free.
Breakfast
A buffet breakfast is served at affordable prices.
Children & extra beds
There are no extra beds provided in a room.  There are no cots provided in a room. 
Pets
Pets are allowed on request.
Number of floors:
4
Number of rooms:
76

Reviews and Ratings

Feedback about Home2 Suites By Hilton Sioux Falls Sanford Medical Center from previous guests about their experience.
Review score
Based on 113 verified reviews
9.0 /10
Perfect
90 %
Recommend
Cleanliness
9.0/10
Comfort
9.2/10
Facilities
9.1/10
Free WiFi
6.2/10
Location
9.2/10
Staff
9.3/10
Value for money
8.5/10
Pros
Full kitchen
Great staff
Clean pool
Hospital access
Cons
Food stains
Stray hairs
Guest reviews
based on 111 reviews
8.9/10
No reviews yet on our siteUnfortunately, our guests have not yet left any reviews for this hotel, but you can read reviews from Booking.com.
Open reviews
FAQs
About Home2 Suites By Hilton Sioux Falls Sanford Medical Center
What is the distance from Home2 Suites By Hilton Sioux Falls Sanford Medical Center to Sioux Falls Regional Airport?
The hotel is located 4 km from Sioux Falls Regional Airport.
What are the check-in and check-out times at Home2 Suites By Hilton Sioux Falls Sanford Medical Center?
Check-in is at 15:00 and check-out is at 12:00.
Is parking available at Home2 Suites By Hilton Sioux Falls Sanford Medical Center?
Public parking is available on-site for free without the need for a reservation.
What kind of room amenities can guests expect at Home2 Suites By Hilton Sioux Falls Sanford Medical Center?
Each room includes a flat-screen TV, air conditioning, a kitchen with a refrigerator, microwave, and cookware, as well as complimentary Wi-Fi.
What dining options are available at Home2 Suites By Hilton Sioux Falls Sanford Medical Center?
Buffet and American breakfast options are available for an additional charge.
What leisure facilities does Home2 Suites By Hilton Sioux Falls Sanford Medical Center feature?
The hotel features an indoor saline swimming pool, hot tub, and a 24-hour fitness center.
What are some nearby attractions to Home2 Suites By Hilton Sioux Falls Sanford Medical Center?
Nearby attractions include Falls Park (6 minutes away), Denny Sanford Premier Center (6 minutes away), and the Sioux Empire Medical Museum (5 minutes' walk).
Does Home2 Suites By Hilton Sioux Falls Sanford Medical Center offer business services?
The hotel provides a business centre with meeting facilities and complimentary Wi-Fi.
What unique features does Home2 Suites By Hilton Sioux Falls Sanford Medical Center offer?
The hotel includes a Spin2Cycle facility, combining laundry and fitness options, alongside a complimentary grocery delivery service to guest suites.
Is there a smoking area at Home2 Suites By Hilton Sioux Falls Sanford Medical Center?
The hotel is a non-smoking property.
What types of guests does Home2 Suites By Hilton Sioux Falls Sanford Medical Center cater to?
The hotel targets business and family travelers, especially those visiting the Sanford Medical Center.
Are there any restaurants within walking distance of Home2 Suites By Hilton Sioux Falls Sanford Medical Center?
Restaurants within 1 km include Toppers Pizza, Taco John's, Abelardo's Mexican Food, Domino's Pizza, and Pho Quynh.

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