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From166US$ /night
Check-in
28Nov2025Select date
Check-out
29Nov2025Select date
Rooms and Guests2 Guests, 1 Room
Key details

About the Hotel

1120 S Grange Avenue, Sioux Falls, South Dakota, United States, 57105
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The 3-star smoke-free Home2 Suites By Hilton Sioux Falls Sanford Medical Center hotel is located within 5 minutes' walk of the Sioux Empire Medical Museum and features 24-hour reception and wake-up service for guests' convenience. Located just 1.9 km from Michelangelo's David replica, this Sioux Falls hotel features luggage storage.

Location

The hotel is situated in the centre of Sioux Falls, near restaurants and theatres. The Lucky Lady Casino in Sioux Falls is a short way from the Home2 Suites.

The accommodation also takes you to USS South Dakota Battleship Memorial, which is approximately a 10-minute drive away.

Rooms

The 76 rooms at this Sioux Falls hotel are equipped with comforts such as ironing equipment and air conditioning, as well as a flat-screen TV with satellite channels and a radio. A refrigerator, a stove top, and kitchenware are available upon request.

Eat & Drink

Situated just 1.2 km from Home2 Suites By Hilton Sioux Falls Sanford Medical Center hotel, the quick bites Giliberto's Mexican Taco Shop offers a Mexican menu.

Leisure & Business

The property has an indoor pool and a fitness suite. Also, at this hotel, guests can take advantage of a sports complex provided onsite. Finally, the Home2 Suites Sioux Falls houses a business centre featuring a xerox and a work desk.

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Select your room type

The hotel provides many room choices—family rooms, doubles, and pet-friendly suites—with breakfast, free cancellation, and special offers
King Studio Suite Non-Smoking
2 persons
40 m² 
1 King-size bed
Heating
Air conditioning
Queen Studio Two Queen Beds Non-Smoking
2 persons
40 m² 
2 King Size Beds
Heating
Air conditioning
King Studio Suite Hearing Access or Non-Smoking
2 persons
40 m² 
1 King-size bed
Heating
Air conditioning
Queen Studio Two Queen Beds Mobility Access or Non-Smoking
2 persons
40 m² 
2 King Size Beds
Heating
Air conditioning
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Rates & availability calendar

See current prices and availability for your chosen dates!

Local transport and travel tips

Overview of transport options available

City Centre
Sioux Falls800 m
Airports
Sioux Falls Regional (FSD) 7.9 km
Stronsay (soy) 86.3 km

Facilities

Hotels feature amenities designed to keep both you and your pet comfortable

General

  • No smoking on site
  • Free Wi-Fi
  • Parking
  • 24-hour reception
  • Express check-in/ -out
  • Pets allowed
  • Rooms/ Facilities for disabled
  • Wheelchair access
  • Luggage storage
  • Lift

Sports & Fitness

  • Fitness centre

Guest Parking

  • Cookware/ Kitchen utensils

Services

  • Laundry

Business

  • Business centre
  • Fax/Photocopying

Spa & Leisure

  • Indoor swimming pool
  • Jacuzzi

Room features

  • Air conditioning
  • Heating
  • Sitting area
  • Tea and coffee facilities
  • Ironing facilities

Bathroom

  • Free toiletries

Self-catering

  • Cookware/ Kitchen utensils

Media

  • Flat-screen TV
  • AM/FM alarm clock

Room decor

  • Curtains
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Hotel location

1120 S Grange Avenue, Sioux Falls, South Dakota, United States, 57105
Map view
1120 S Grange Avenue, Sioux Falls, South Dakota, United States, 57105
Nearby
1305 W 18th St In the Sanford USD Medical Center
Sioux Empire Medical Museum
290 m
1001 SW Avenue
Sioux Falls Stadium
530 m
Restaurants
The Co-op of Sioux Falls
860 m
410 W 18th St
Azteca
1.1 km
811 S Minnesota Ave
Toppers Pizza
1.1 km
817 S Minnesota Ave
Taco John's
1.0 km
1100 S Minnesota Ave
Papa John's Pizza
1.1 km
711 S Minnesota Ave
Abelardo's Mexican Food
1.1 km
1200 S Minnesota Ave
Pho Quynh
960 m
1100 W 12th St
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Check-in
28Nov2025Select date
Check-out
29Nov2025Select date
Rooms and Guests2 Guests, 1 Room